Question

Assertion: Cell lines derived from the primary culture of normal cells are finite cell line.

Reason: Some cells of the finite cell line undergoes transformation and retain the ability to divide indefinitely.

(a) Both assertion and reason are true and the reason is the correct explanation of the assertion.

(b) Both assertion and reason are true but the reason is not the correct explanation of the assertion.

(c) Assertion is true but reason is false.

(d) Both assertion and reason are false.

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Answer

(b) Both assertion and reason are true but the reason is not the correct explanation of the assertion.

Explanation: The assertion is true because cell lines derived from primary cultures of normal cells are indeed finite; they have a limited number of cell divisions before they senesce. However, the reason given relates to the transformation of some cells within finite cell lines which then may give rise to continuous cell lines. While it's true that some cells might undergo transformations and become continuous cell lines, this characteristic is not the explanation for why the original finite cell lines derived from primary cultures have a limited number of cell divisions. These are two distinct properties of different types of cell lines.


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